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Teen Substance Use Is Near Historic Lows — but Fentanyl Has Changed the Risk

There is genuinely good news about teen substance use in America. According to the most recent Monitoring the Future survey — an annual study conducted by the National Institute on Drug Abuse (NIDA) and the University of Michigan — adolescent drug and alcohol use remained at or near historic lows for the fifth consecutive year in 2025. But that progress exists alongside a newer danger: fentanyl-contaminated counterfeit pills that can be lethal even on a first use, and that young people are increasingly encountering through social media. Understanding both sides of this picture is essential for parents, educators, and anyone who cares about the next generation.

What the data shows: most teens are choosing not to use substances

The 2025 Monitoring the Future survey collected responses from more than 23,700 students across 270 schools nationwide. The headline finding is striking: approximately 91% of 8th graders, 82% of 10th graders, and 66% of 12th graders reported abstaining from marijuana, alcohol, and nicotine in the prior 30 days.

Looking at each substance individually:

Researchers caution that these numbers reflect self-reported use among enrolled students and are snapshots, not guarantees of permanent progress. But the five-year trend is meaningful and reflects the impact of prevention investments, awareness campaigns, and community-level work.

The fentanyl exception: why a single pill can be fatal

Here is where the good news becomes complicated. Even as overall teen drug use has fallen, overdose deaths among young people rose sharply between 2020 and 2022 before beginning to decline — and fentanyl is the reason. According to CDC data, roughly 75% of overdose deaths among youth ages 10–19 between 2020 and 2024 involved fentanyl, often hidden in counterfeit pills that looked like legitimate prescription medications such as Adderall, Xanax, or Percocet.

This matters because many of these young people were not regular drug users. They may have obtained what they believed was a single anxiety pill or a study aid from a friend or through social media — and encountered a lethal dose of illicitly manufactured fentanyl instead. The Drug Enforcement Administration found that in 2023, seven out of every ten counterfeit opioid pills seized contained a potentially deadly dose of fentanyl. Just two milligrams — an amount smaller than a few grains of salt — can be fatal.

Nearly half of teenagers are unaware that counterfeit prescription pills can contain lethal amounts of fentanyl, according to research cited by CDC. That knowledge gap is itself a public health problem — and closing it is one of the most important things adults can do.

Mental health is the missing piece

Substance use among young people rarely happens in isolation. The KFF estimates that approximately 19% of adolescents experience moderate to severe anxiety, and about 2 million adolescents in the U.S. have a substance use disorder. Research consistently shows that untreated anxiety, depression, trauma, and ADHD raise the risk of substance use as teens seek relief from difficult feelings.

This means prevention and early intervention are two sides of the same coin. Schools, pediatricians, and families who address mental health early — making it as routine to talk about as physical health — are also reducing the conditions that make substance use more likely.

What works: evidence-based prevention

Decades of research have identified specific approaches that reliably reduce youth substance use:

What parents can do right now

If you or a young person needs help: Call or text 988 (Suicide and Crisis Lifeline — also for mental health crises) or call SAMHSA's free, confidential National Helpline at 1-800-662-4357 to find treatment and recovery support services near you, 24 hours a day, 365 days a year.

At Empower Next Project, we believe that protection and hope go hand in hand. The data showing five years of declining teen substance use is a reminder that prevention works — and that the communities investing in young people are making a measurable difference. Our Empower Next Breath and Empower Next Steps programs extend this work into homes and communities across our region.

Sources

  1. NIH/NIDA, "Reported use of most drugs remains low among U.S. teens" (December 2025). nih.gov
  2. NIDA, Monitoring the Future Survey (annual). nida.nih.gov/research-topics/trends-statistics/monitoring-future
  3. CDC, "Drug Overdose Deaths Among Persons Aged 10–19 Years — United States, July 2019–December 2021," MMWR Vol. 71, No. 50. cdc.gov/mmwr
  4. CDC, ENGAGE: Evidence-Based Strategies to Prevent Youth Substance Use. cdc.gov/overdose-prevention
  5. CDC, Free Mind — Fake Pills Fact Sheet for Youth. cdc.gov/free-mind
  6. SAMHSA, "Talk. They Hear You." Campaign. samhsa.gov/substance-use/prevention/talk-they-hear-you
  7. SAMHSA, Prevention of Substance Use. samhsa.gov/substance-use/prevention/substance-use-disorders
  8. KFF, "5 Key Facts on Adolescent Mental Health and Substance Use Disorders." kff.org
  9. SAMHSA National Helpline: 1-800-662-HELP (4357). samhsa.gov/find-help/national-helpline

This article is educational and is not a substitute for professional medical or mental health advice. In an emergency, always call 911. For substance use and mental health support, call or text 988 or call SAMHSA's helpline at 1-800-662-4357.